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Pharmacocinétique / les fractions


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Just now, natacha said:

Bonjour, 

Est ce que quelqu'un pourrait m'expliquer les fractions : F, fu et fe, ? je fais souvent des fautes et je les confonds

Salut,

F = coefficient de biodisponibilité = ASC(oral)/ASC(IV)

Fe = fraction non metabolisée retrouvée dans les urines : CLr = CL*fe

Fu = fraction libre : CLfg = 120*fu

J'espere que c'est plus clair

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Il y a 1 heure, Aaronigashima a dit :

Salut,

F = coefficient de biodisponibilité = ASC(oral)/ASC(IV)

Fe = fraction non metabolisée retrouvée dans les urines : CLr = CL*fe

Fu = fraction libre : CLfg = 120*fu

J'espere que c'est plus clair

 Rien a redire ! 

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